Chlorpheniramine Maleate+dextromethorphan+phenylephrine
About Chlorpheniramine Maleate+dextromethorphan+phenylephrine
Chlorpheniramine Maleate+dextromethorphan+phenylephrine is used to treat dry cough. Coughing is the body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. A dry cough is tickly and doesn't produce any viscous or thick mucus, while a chesty cough (wet cough) means mucus or sputum is created to help clear the airways.
Chlorpheniramine Maleate+dextromethorphan+phenylephrine is a combination of Chlorpheniramine, Phenylephrine, and Dextromethorphan. Chlorpheniramine works by blocking the action of histamine. Phenylephrine helps in shrinking the blood vessels located in the nasal passage. Dextromethorphan works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce a cough.
Some people may experience dry mouth, throat, or nose, as well as drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation. Most of these side effects do not require medical attention. However, if the side effects persist or worsen, please consult your doctor.
If you are pregnant or breastfeeding, it is advised to inform your doctor before using Chlorpheniramine Maleate+dextromethorphan+phenylephrine. Avoid using Chlorpheniramine Maleate+dextromethorphan+phenylephrine if you have taken monoamine oxidase inhibitors in the past 14 days. If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, inform your doctor before taking it.
Uses of Chlorpheniramine Maleate+dextromethorphan+phenylephrine
Medicinal Benefits
- Chlorpheniramine Maleate+dextromethorphan+phenylephrine contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan used to treat dry cough.
- Chlorpheniramine maleate helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness.
- Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose.
- Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough.
- Thus, Chlorpheniramine Maleate+dextromethorphan+phenylephrine helps to relieve overall cough, cold and allergic symptoms.
Directions for Use
- Chlorpheniramine Maleate+dextromethorphan+phenylephrine can be taken with or without food as advised by the doctor.
- Follow your doctor’s instructions on the dosage and timing of this medication.
- Measure the prescribed dose using a measuring cup and administer it orally.
- Shake well before each use.
Storage
Side Effects of Chlorpheniramine Maleate+dextromethorphan+phenylephrine
- Dry mouth, throat or nose
- Drowsiness
- Dizziness
- Blurred vision
- Headache
- Constipation
- Restlessness or excitation
- Loss of appetite
Drug Warnings
- If you are allergic to Chlorpheniramine Maleate+dextromethorphan+phenylephrine or any other medicines, please tell your doctor.
- If you are pregnant or breastfeeding, it is advised to inform your doctor before using it.
- Chlorpheniramine Maleate+dextromethorphan+phenylephrine is not recommended for children below 12 years of age.
- If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking this medicine.
- Avoid taking Chlorpheniramine Maleate+dextromethorphan+phenylephrine if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days.
- If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Chlorpheniramine Maleate+dextromethorphan+phenylephrine.
Drug Interactions
Drug-Drug Interaction: Chlorpheniramine Maleate+dextromethorphan+phenylephrine may have interaction with anti-allergic drugs (diphenhydramine), anti-psychotic (escitalopram, desvenlafaxine, vilazodone), pain killer (aspirin), cold medicines (acetaminophen), antibiotics (amoxicillin), anti-depressants (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), beta-blockers (metoprolol, atenolol), muscle relaxants (carisoprodol, cyclobenzaprine).
Drug-Food Interaction: Chlorpheniramine Maleate+dextromethorphan+phenylephrine may interact with alcohol. Therefore, avoid alcohol consumption with Chlorpheniramine Maleate+dextromethorphan+phenylephrine as it may increase the risk of adverse effects such as drowsiness, dizziness or difficulty in concentrating.
Drug-Disease Interaction: Chlorpheniramine Maleate+dextromethorphan+phenylephrine is known to interact in patients with liver or kidney disease, asthma, diabetes, glaucoma, cardiovascular diseases, enlarged prostate gland, chronic bronchitis or emphysema (a lung condition causing shortness of breath).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorAvoid consumption of alcohol with Chlorpheniramine Maleate+dextromethorphan+phenylephrine as it may increase drowsiness. Please consult a doctor before consuming alcohol with Chlorpheniramine Maleate+dextromethorphan+phenylephrine.
Pregnancy
consult your doctorThe safety of Chlorpheniramine Maleate+dextromethorphan+phenylephrine in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.
Breast Feeding
consult your doctorIt is unknown whether Chlorpheniramine Maleate+dextromethorphan+phenylephrine is excreted in human milk. Chlorpheniramine Maleate+dextromethorphan+phenylephrine is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.
Driving
cautionChlorpheniramine Maleate+dextromethorphan+phenylephrine may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Chlorpheniramine Maleate+dextromethorphan+phenylephrine.
Liver
cautionTake Chlorpheniramine Maleate+dextromethorphan+phenylephrine with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake Chlorpheniramine Maleate+dextromethorphan+phenylephrine with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
consult your doctorChlorpheniramine Maleate+dextromethorphan+phenylephrine is not recommended for children below 4 years of age. However, please consult a doctor before using Chlorpheniramine Maleate+dextromethorphan+phenylephrine in children.
Habit Forming
Diet & Lifestyle Advise
- Avoid dairy products such as milk, as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough.
- Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
- Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.
Special Advise
- Do not use Chlorpheniramine Maleate+dextromethorphan+phenylephrine only to make a child sleepy.
- Contact a doctor if your symptoms do not improve even after 7 days.
- Contact a doctor immediately if you develop fever, rash or headaches after taking Chlorpheniramine Maleate+dextromethorphan+phenylephrine.
Patients Concern
Disease/Condition Glossary
Cough: Coughing is the body's way of clearing irritants from the airways (such as allergens, mucus, or smoke) and preventing infection. Coughs can be productive or dry. A productive cough (wet cough) causes sputum (phlegm, mucus, and other matter) to be expelled from the lungs. Coughing is commonly caused by an allergic reaction or a viral infection, but coughing up mucus could indicate a respiratory infection. You may have a bacterial infection in your airways if you cough up thick, solid white mucus. If your mucus is clear or light-coloured, you may have allergies or minor respiratory infections, whereas yellow or green mucus indicates a respiratory infection.
FAQs
Chlorpheniramine Maleate+dextromethorphan+phenylephrine belongs to a class of medication called 'cough and cold preparations primarily used to treat dry cough. Coughing (dry or productive) is the body way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection.
Chlorpheniramine Maleate+dextromethorphan+phenylephrine contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan. Chlorpheniramine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine is a decongestant that helps in shrinking the blood vessels located in the nasal passage, thereby reducing stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough.
No, you should not take Chlorpheniramine Maleate+dextromethorphan+phenylephrine if you need to undergo surgery as it may lead to excessive drowsiness and sleepiness when given along with anaesthesia. Therefore, if you are about to undergo any surgery, please inform your doctor that you are taking Chlorpheniramine Maleate+dextromethorphan+phenylephrine. Your doctor may advise you to stop taking Chlorpheniramine Maleate+dextromethorphan+phenylephrine 72 hours before the surgery.
It is not recommended to take Chlorpheniramine Maleate+dextromethorphan+phenylephrine along with any anti-depressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side-effects or any drug interaction. Also, Chlorpheniramine Maleate+dextromethorphan+phenylephrine should be taken at least 15 days after your last dose of anti-depressants.
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take Chlorpheniramine Maleate+dextromethorphan+phenylephrine and skip the missed dose. Do not take extra medicine to make up for the missed dose.
Chlorpheniramine Maleate+dextromethorphan+phenylephrine should be used with caution and only when prescribed by a doctor in patients with glaucoma, as Chlorpheniramine Maleate+dextromethorphan+phenylephrine may rarely worsen the symptoms of glaucoma.
